Searchable abstracts of presentations at key conferences in endocrinology

ea0099oc3.6 | Oral Communications 3: Adrenal and Cardiovascular Endocrinology | Part I | ECE2024

Multiple dosing of immediate-release hydrocortisone is associated with a greater risk of hypothalamic-pituitary-adrenal axis suppression when compared to low-dose prednisolone when weaning in steroid-induced adrenal insufficiency

Mifsud Simon , Mifsud Emma Louise , Newell-Price John , Ross Richard , Debono Miguel

Background: Long-term glucocorticoids can result in iatrogenic Cushing’s syndrome with adrenal suppression. Most patients reactivate their hypothalamic-pituitary-adrenal axis once they’re weaned off glucocorticoids. During glucocorticoid withdrawal, many clinicians switch patients to hydrocortisone to benefit from its short half-life1. However, in some patients, hypothalamic-pituitary-adrenal axis recovery is delayed despite the above. It is unclear whethe...